Recombinant MBP antibody

Catalog No. ABIN7543255

This anti-MBP antibody is a Mouse Monoclonal antibody detecting MBP in ELISA. Suitable for Human.

Quick Overview for Recombinant MBP antibody (ABIN7543255)

Target: MBP (Myelin Basic Protein (MBP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MBP antibody is un-conjugated

Application: ELISA

Clone: F28C4

Product Details anti-MBP Antibody

Purpose: Anti-Myelin basic protein [F28C4], Mouse IgG2a, lambda

Specificity: This antibody binds human myelin basic protein (MBP), acetyl residues 1-9 (ASQKRPSQR). The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing PL/J mice with MBP acetyl residues 1-9.

Isotype: IgG2a lambda

Application Details

Application Notes: This antibody shares a cross reactive idiotpe with the TCRs, possibly as a result of having similar fine epitope specificity and sequence homology (PMID: 7517973). This antibody can be used for the detection of MBP in a solution using ELISA (PMID: 8567971).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin basic protein

Background: MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein

UniProt: P02686